REVIEW Hexestrol is a carcinogenic non-steroidal synthetic anabolic agent, (estrogen) that inhibits microtubule polymerization and the formation of ribbon structures, while also an inhibitor of lipid peroxidation.
REFERENCES
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Aboul-Enein, Hassan Y.; Lotfi, Essam A.; Mohamed, Mohamed E. Hexestrol, Analytical Profiles of Drug Substances (1982), 11, 347-74.
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Neumann F. Pharmacological and endocrinological studies on anabolic agents. Environ Qual Saf Suppl. 1976;(5):253-64.
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Liehr JG, Ballatore AM, Dague BB, Ulubelen AA. Carcinogenicity and metabolic activation of hexestrol. Chem Biol Interact. 1985 Oct;55(1-2):157-76.
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Sato Y, Murai T, Oda T, Saitô H, Kodama M, Hirata A. Inhibition of microtubule polymerization by synthetic estrogens: formation of a ribbon structure. J Biochem. 1987 May;101(5):1247-52.
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