638-94-8 Desonide AKSci J10522
 
 
Loading Please Wait...
  J10522    
Desonide, 99% (HPLC)
 
Locapred
Topifug
Tridesilon
IDENTITY
CAS Number:638-94-8
MDL Number:MFCD00866151
MF:C24H32O6
MW:416.51
EINECS:211-351-6
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:99% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:260-283°C
Optical Rotation:+119.0°- +124.0° (c=0.5, MeOH)
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: 83mg/mL; H2O: <1mg/mL; EtOH: 43mg/mL
Application(s):Anti-Inflammatory Agent
Form:Free Base

REVIEW
 A low-potency topical corticosteroid that is primarily used to treat atopic dermatitis (eczema), seborrheic dermatitis, contact dermatitis and psoriasis in both adults and children.

REFERENCES
[1]Liu Z, Shi Q, Ding D, Kelly R, Fang H, Tong W (2011). Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). PLoS Comput Biol. 7(12):e1002310. PMID 22194678.
[2] Yentzer BA, Camacho FT, Young T, Fountain JM, Clark AR, Feldman SR (2010). Good adherence and early efficacy using desonide hydrogel for atopic dermatitis: results from a program addressing patient compliance. J Drugs Dermatol. 9(4):324-9. PMID 20514788.
[3] Sax, K. J.; Steroids 1965, V5(3), P345-59
[4] Mantica, L.; Arzneimittel-Forschung 1970, V20(1), P109-10

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of May 3, 2024


Download SDS Request COA

All products are stocked and shipped from San Francisco Bay Area, California, USA.

⚠️
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.


CATEGORIES
 APIs and Bioactives > Steroid Hormones


PubChem