67560 Prednisolone acetate - AK Scientific
 
 
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  Catalog ID # 67560
Prednisolone acetate
, 98% (HPLC)
 
21-Acetoxy-1,4-pregnadiene-11beta,17alpha-diol-3,20-dione
Omnipred
Prednisolone 21-acetate




IDENTITY
CAS Registry #:[52-21-1]
MDL Number:MFCD00037710
MF:C23H30O6
MW:402.48
EINECS:200-134-1
BRN:3111798
SPECIFICATIONS & PROPERTIES
Purity:98% (HPLC)
Available Spectra:LCMS, HPLC, Polarimetry
Physical Form:White to off-white powder
Melting Point:245-252°C
Optical Rotation:+112° (c=1, Dioxane)
Shipping:Regulated for Shipping.
UN #:2811
Hazard Class:6.1
Packing Group:III

BIOLOGICAL INFO
Solubility:CHCl3:MeOH (1:1): 50mg/mL
Application(s):Anti-Inflammatory Agent; Glucocorticoid Receptors (GR)
Form:Free Base

REVIEW

 A synthetic glucocorticoid, a derivative of cortisol, which is used to treat a variety of inflammatory and auto-immune conditions. Prednisolone irreversibly binds with glucocorticoid receptors (GR) alpha and beta for which they have a high affinity.

REFERENCES
[1]McLean NJ, Ward DA, Hendrix DV, Vaughn RK (2012). Effects of one-week versus one-day preoperative treatment with topical 1% prednisolone acetate in dogs undergoing phacoemulsification. J Am Vet Med Assoc. 240(5):563-9. PMID 22332625.
[2] Nien CJ, Flynn KJ, Chang M, Brown D, Jester JV (2011). Reducing peak corneal haze after photorefractive keratectomy in rabbits: prednisolone acetate 1.00% versus cyclosporine A 0.05%. J Cataract Refract Surg. 37(5):937-44. PMID 21406325.

Risk Description(s)
R25:Toxic if swallowed.

Safety Description(s)
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).



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CURRENT AS OF: March 27, 2015
Availability
1. In Stock: Order today by 4 PM PT and ships today from San Francisco, CA, USA
2. Backordered: Please contact us for availability.
3. If Bulk (kg) is Backordered, sizes less than 1kg may be available.
4. All prices FOB San Francisco, CA, USA
HazMat
HazMat shipping information is based on IATA/DOT regulations. For reference only.
1. Not Required: Not regulated by IATA/DOT. Normal shipping for Ground and Express.
2. Required for Express: HazMat shipping via Express. Normal shipping for continental Ground.

SDS

 67560_SDS.pdf

CATEGORIES

 APIs and Bioactives > Immunomodulators

USEFUL LINKS

  PubChem