1259296-46-2 MPI_5a AKSci SYN3040
 
 
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  SYN3040    
MPI_5a
, >95%
 
MPI5a




IDENTITY
CAS Number:1259296-46-2
MF:C16H17N3O3
MW:299.33
SPECIFICATIONS & PROPERTIES
Purity:>95%
Long-Term Storage:Store at room temperature

BIOLOGICAL INFO
Solubility:Soluble in DMSO

REVIEW

 MPI_5a is a potent selective inhibitor of HDAC6, and poorly blocks other HDAC enzymes. HDAC6 is a predominantly cytoplasmic enzyme that targets α-tubulin, cortactin, and heat shock protein 90, and other substrates. MPI-5a has an IC50 of 36 nM in tumour cell models and inhibits the acetylation of tubulin in cells with an IC50 value of 210 nM.

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of March 19, 2019


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