874119-56-9 GSK-25 AKSci SYN1124
 
 
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  SYN1124    
GSK-25
, >95%
 
GSK25




IDENTITY
CAS Number:874119-56-9
MDL Number:MFCD18782716
MF:C24H16Cl2F2N6O
MW:513.33
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:>95%
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:15 mM in DMSO
Application(s):RSK1 - p70S6K

REVIEW

 GSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K (RSK1 IC50 of 398 nM, p70S6K IC50 of 1000nM), and a dramatically improved P450 profile (>2.2 uM at all isozymes tested).

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of June 22, 2024


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