212844-54-7 Purvalanol B AKSci SYN1070
 
 
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  SYN1070    
Purvalanol B, 98%
 
NG95
IDENTITY
CAS Number:212844-54-7
MDL Number:MFCD04118312
MF:C20H25ClN6O3
MW:432.9
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98%
Long-Term Storage:Store long-term at -20°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO 112mg/mL, Ethanol 4mg/mL
Application(s):CDK2 - CDK7 - CDK5 - CDK4

REVIEW
 Purvalanol B is a cyclin-dependent kinase inhibitor with IC50 values of 6, 6, 9, > 10,000, and 6 nM for cdc2/cyclin B, cdk2/cyclin A, cdk2/cyclin E, cdk4/cyclin D1 and cdk5-p35 respectively. Purvalanol B has also been shown to have anti-proliferative properties, mediated by p42/p44 MAPK.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of April 18, 2024


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