1235-82-1 Biperiden hydrochloride AKSci J98893
 
 
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  J98893    
Biperiden hydrochloride
, 95%
 
Akineton hydrochloride




IDENTITY
CAS Number:1235-82-1
MDL Number:MFCD00797516
MF:C21H29NO.HCl
MW:347.92
EINECS:214-976-2
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:95%
Physical Form (at 20°C):Solid
Melting Point:241-252°C
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: >20 mg/mL; H2O: insoluble
Application(s):Antiparkinson Agent; Muscarinic Antagonist; Parasympatholytic
Form:HCl salt

REVIEW

 An antiparkinsonian agent of the anticholinergic type. Biperiden has an atropine-like blocking effect on all peripheral structures which are parasympathetic-innervated. It also has a prominent central blocking effect on M1 receptors.

REFERENCES
[1]Klinkenberg I, Blokland A (2011). A comparison of scopolamine and biperiden as a rodent model for cholinergic cognitive impairment. Psychopharmacology (Berl). 215(3):549-66. PMID 21336581.
[2] Asth L, Lobão-Soares B, André E, Soares Vde P, Gavioli EC (2012). The elevated T-maze task as an animal model to simultaneously investigate the effects of drugs on long-term memory and anxiety in mice. Brain Res Bull. 87(6):526-33. PMID 22394406.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H302

Precautionary Statements
P264; P270; P301+P312; P330; P501


Current as of April 20, 2024


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