102-65-8 Sulfaclozine sodium monohydrate AKSci J61945
 
 
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  J61945    
Sulfaclozine sodium monohydrate, 95%
 
Sulfachloropyrazine sodium
IDENTITY
CAS Number:102-65-8
MDL Number:MFCD28954637
MF:C10H9ClN4O2SNa
MW:306.70
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:95%
Physical Form (at 20°C):Solid
Melting Point:315°C
Density:1.6
Refractive Index:1.68
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Application(s):An antiprotozoal useful in coccidiosis research

REVIEW
 Sulfachloropyrazine sodium (also known as sulfaclozine sodium) is an oral broad-spectrum sulfonamide antibiotic intended for treatment of coccidiosis and specific bacteral diseases in poultry. Sulfachloropyrazine sodium is indicated for treatment of coccidiosis in poultry due to infection with Eimeria species, fowl typhoid due to infection with Salmonella gallinarum and fowl cholera due to infection with Pasteurella multocida. Like all sulfonamides, sulfachloropyrazine is a competitive antagonist of para-aminobenzoic acid (PABA), a precursor of folic acid, in protozoa and bacteria. Folic acid is a coenzyme necessary for the synthesis of nucleic acid, hence sensitive species do not multiply in the presence of sulfachloropyrazine sodium. It has been found to be effective against murine toxoplasmisis.

REFERENCES
[1]Varga, Istvan; Papp, Zoltan; Gyenes, Janos Studies on the efficacy of Esb3 against Eimeria stiedai in rabbits Magyar Allatorvosok Lapja (1986), 41(5), 305-9.
[2] Panda, D. N.; Mishra, A.; Misra, S. C.; Rao, A. G. Efficacy of Esb3 in the treatment of experimental Eimeria tenella infection in broiler chickens Indian Veterinary Journal (1999), 76(3), 199-201.
[3] Sentepe, Ismail; Eraslan, Gokhan Pharmacokinetic of sulfaclozine in broiler chickens Food and Chemical Toxicology (2010), 48(1), 448-451.
[4] Haritova, Aneliya M.; Lashev, Lubomir D.; Koinarski, Vencislav C. Sulfachloropyrazine disposition in Eimeria tenella infected chickens Veterinarski Arhiv (2013), 83(2), 211-222.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of April 23, 2024


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All products are stocked and shipped from San Francisco Bay Area, California, USA.

⚠️
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.


CATEGORIES
 APIs and Bioactives > Antibacterials, Antiparasitics, Veterinary


PubChem
  @PubMed