976-71-6 Spironolactone Related Compound A AKSci J10438
 
 
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  J10438    AKSci Reference Standard
Spironolactone Related Compound A
, 99% (HPLC)
 
(17a)-17-Hydroxy-3-oxopregna-4,6-diene-21-carboxylic acid gamma-lactone
Canrenone




IDENTITY
CAS Number:976-71-6
MDL Number:MFCD00071735
MF:C22H28O3
MW:340.46
EINECS:213-554-5
SPECIFICATIONS & PROPERTIES
Purity:99% (HPLC)
Spectra:FT-IR, LCMS, HPLC, Polarimetry
Physical Form:Yellow powder
Melting Point:160-167°C
Optical Rotation:+24 ~ +30° (c=1, CHCl3)
Long-Term Storage:Store at room temperature

REVIEW

 Aldosterone antagonist.

REFERENCES
[1]Struthers, A., et al.: Heart, 92, 1728 (2006)
[2] Sadee, W., et al.: J. Pharmacol. Exp. Ther., 185, 686 (1973)
[3] Pitt, B., et al.: Circulation, 108, 1831 (2003)
[4] Silvestre, J., et al.: J. Biol. Chem., 273, 4883 (1998)

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H316; H351; H411

Precautionary Statements
P273; P281


Current as of July 14, 2020

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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CATEGORIES

 APIs and Bioactives > Diuretics, Steroid Hormones


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