173903-47-4 Tizoxanide AKSci 8987AA
 
 
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  8987AA    
Tizoxanide, 98% (HPLC)
 
2-Hydroxy-N-(5-nitrothiazol-2-yl)benzamide
IDENTITY
CAS Number:173903-47-4
MDL Number:MFCD07484970
MF:C10H7N3O4S
MW:265.25
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:268-274°C
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

REVIEW
 Tizoxanide is the active metabolite of nitazoxanide, an anti-infective that has been approved for the treatment of diarrhea caused by Giardia lamblia or Crytosporidium parvum. Tizoxanide is active against anaerobic bacteria, protozoan parasites, and viruses. It reduces the growth of the disease-causing parasites, L. mexicana and T. cruzi, in vitro (IC50s = 6.2 and 17.5 μM, respectively), inhibits influenza A replication (EC50s = 0.3-1 μM), and inhibits hepatitis B and hepatitis C virus replication (EC50s both = 0.15 μM).

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of April 25, 2024


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