V0098 (4S)-3-[5-(4-Fluorophenyl)-1,5-dioxopenyl]-4-phenyl-2-oxazolidinone - AK Scientific
 
 
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  Catalog ID # V0098
(4S)-3-[5-(4-Fluorophenyl)-1,5-dioxopenyl]-4-phenyl-2-oxazolidinone
, 98%
 



IDENTITY
CAS Registry #:[189028-93-1]
MDL Number:MFCD08061377
MF:C20H18FNO4
MW:355.36
SPECIFICATIONS & PROPERTIES
Purity:98%
Physical Form:White crystalline powder
Melting Point:88-92°C
Shipping:Not Regulated for Shipping

REVIEW

 (4S)-3-[5-(4-Fluorophenyl)-1,5-dioxopenyl]-4-phenyl-2-oxazolidinone is a key advanced intermediate used in the preparation of ezetimibe.

REFERENCES
[1]Thiruvengadam, Tiruvettipuram K.; Fu, Xiaoyong; Tann, Chou-Hong; McAllister, Timothy L.; Chiu, John S.; Colon, Cesar Process for the synthesis of azetidinones and intermediates for use as hypocholesterolemics PCT Int. Appl. (2000), WO 2000034240 A1 20000615.
[2] Thiruvengadam, Tiruvettipuram K.; Fu, Xiaoyong; Tann, Chou-hong; McAllister, Timothy L.; Chiu, John S.; Colon, Cesar Process for the synthesis of azetidinones U.S. (2001), US 6207822 B1 20010327.
[3] Thiruvengadam, Tiruvettipuram K.; Chiu, John S.; Fu, Xiaoyong; McAllister, Timothy L. Process for the synthesis of azetidinones U.S. Pat. Appl. Publ. (2006), US 20060135755 A1 20060622.
[4] Barden, Timothy C.; Lee, Peter; Martinez, Eduardo J.; Schairer, Wayne C.; Talley, John J. Processes for production of phenolic 4-biphenylylazetidin-2-ones PCT Int. Appl. (2006), WO 2006122216 A2 20061116.

Risk Description(s)
R36/37/38:Irritating to eyes, respiratory system and skin

Safety Description(s)
S24/25:Avoid contact with skin and eyes.


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CURRENT AS OF: May 29, 2015
Availability
1. In Stock: Order today by 4 PM PT and ships today from San Francisco, CA, USA
2. Backordered: Please contact us for availability.
3. If Bulk (kg) is Backordered, sizes less than 1kg may be available.
4. All prices FOB San Francisco, CA, USA
HazMat
HazMat shipping information is based on IATA/DOT regulations. For reference only.
1. Not Required: Not regulated by IATA/DOT. Normal shipping for Ground and Express.
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SDS

 V0098_SDS.pdf

CATEGORIES

 APIs and Bioactives > Hypercholesterolemia

USEFUL LINKS

  PubChem