U636 Bucladesine sodium - AK Scientific
 
 
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  Catalog ID # U636
Bucladesine sodium
, 95% (HPLC)
 
Bucladesine
Sodium dibutyryl cAMP
Bucladesine sodium salt
Bucladesine sodium
Actosin
Dibutyryl cyclic-AMP sodium salt




IDENTITY
CAS Registry #:[16980-89-5]
MDL Number:MFCD00005843
MF:C18H23N5NaO8P
MW:491.3675
EINECS:241-059-4
SPECIFICATIONS & PROPERTIES
Purity:95% (HPLC)
Available Spectra:NMR, LCMS, HPLC
Physical Form:White to off-white to beige powder
Long-Term Storage:Store long-term at -20°C
Shipping:Not Regulated for Shipping
Note:Loses 2'-O-butyryl group at pH 8.5. Impurity: =3% N6-monobutyryl-cyclic AMP; =0.5% cyclic AMP and 2'-O-monobutyryl-cyclic AMP

BIOLOGICAL INFO
Solubility:H2O:100mg/mL; DMSO (200mM) or 96% ethanol (25mM).
Application(s):PKA activator; Phosphodiesterase inhibitor
Form:Sodium salt

REVIEW

 Bucladesine is a cyclic nucleotide derivative, mimics the action of endogenous cAMP and is a phosphodiesterase inhibitor. A cell-permeable cAMP analog which preferentially activates cAMP-dependent protein kinase. The products releaes butyrate due to intracellular and extracellular esterase action. Butyrate was shown to have distinct biological effects. The compound is used in a wide variety of research applications because it mimics cAMP and can induce normal physiological responses when added to cells in experimental conditions.

Risk Description(s)
R36/37/38:Irritating to eyes, respiratory system and skin

Safety Description(s)
S24/25:Avoid contact with skin and eyes.


Pricing

CURRENT AS OF: September 27, 2016

Availability
1. Backordered: Please contact us for availability.
2. All prices FOB San Francisco, USA

HazMat
HazMat shipping information is based on IATA/DOT regulations. All of the information is for reference only and subject to change without notice.

Quality
1. All products' quality is guaranteed.
2. Lot-specific spectra and CoA available on request.

Usage
AK Scientific products are intended for Research and Development usage only. The products are not to be used for other purposes, including, but not limited to, human or animal use, or as a component in, a food, drug, medical device (including in vitro diagnostic reagents), cosmetics and pesticides.

The hazards associated with this chemical have not been fully evaluated. This chemical is to be used for research and development purposes only, under the supervision of a technically qualified individual.

AK Scientific is not an EPA registered pesticidal establishment. Our products are not intended for pesticidal applications.

SDS

 U636_SDS.pdf

CATEGORIES

 APIs and Bioactives >
 Nucleobases > Nucleotides

USEFUL LINKS

  PubChem