U636 Bucladesine sodium - AK Scientific
 
 
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  Catalog ID # U636
Bucladesine sodium
, 95% (HPLC)
 
Bucladesine
Sodium dibutyryl cAMP
Bucladesine sodium salt
Bucladesine sodium
Actosin
Dibutyryl cyclic-AMP sodium salt




IDENTITY
CAS Registry #:[16980-89-5]
MDL Number:MFCD00005843
MF:C18H23N5NaO8P
MW:491.3675
EINECS:241-059-4
SPECIFICATIONS & PROPERTIES
Purity:95% (HPLC)
Available Spectra:NMR, LCMS, HPLC
Physical Form:White to off-white to beige powder
Long-Term Storage:Store long-term at -20°C
Shipping:Not Regulated for Shipping
Note:Loses 2'-O-butyryl group at pH 8.5. Impurity: =3% N6-monobutyryl-cyclic AMP; =0.5% cyclic AMP and 2'-O-monobutyryl-cyclic AMP

BIOLOGICAL INFO
Solubility:H2O:100mg/mL; DMSO (200mM) or 96% ethanol (25mM).
Application(s):PKA activator; Phosphodiesterase inhibitor
Form:Sodium salt

REVIEW

 Bucladesine is a cyclic nucleotide derivative, mimics the action of endogenous cAMP and is a phosphodiesterase inhibitor. A cell-permeable cAMP analog which preferentially activates cAMP-dependent protein kinase. The products releaes butyrate due to intracellular and extracellular esterase action. Butyrate was shown to have distinct biological effects. The compound is used in a wide variety of research applications because it mimics cAMP and can induce normal physiological responses when added to cells in experimental conditions.

Risk Description(s)
R36/37/38:Irritating to eyes, respiratory system and skin

Safety Description(s)
S24/25:Avoid contact with skin and eyes.


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CURRENT AS OF: July 7, 2015
Availability
1. In Stock: Order today by 4 PM PT and ships today from San Francisco, CA, USA
2. Backordered: Please contact us for availability.
3. If Bulk (kg) is Backordered, sizes less than 1kg may be available.
4. All prices FOB San Francisco, CA, USA
HazMat
HazMat shipping information is based on IATA/DOT regulations. For reference only.
1. Not Required: Not regulated by IATA/DOT. Normal shipping for Ground and Express.
2. Required for Express: HazMat shipping via Express. Normal shipping for continental Ground.

SDS

 U636_SDS.pdf

CATEGORIES

 Nucleobases > Nucleotides
 APIs and Bioactives >

USEFUL LINKS

  PubChem