[2482-00-0] Agmatine sulfate AKSci P087
 
 
Loading Please Wait...
  Catalog ID # P087
Agmatine sulfate
, 98%
 
1-Amino-4-guanidinobutane sulfate salt
4-Guanidinobutylamine sulfate salt
N-(4-Aminobutyl)guanidine sulfate salt




IDENTITY
CAS Number:[2482-00-0]
MDL Number:MFCD00013109
MF:C5H16N4O4S
MW:228.27
EINECS:219-617-3
SPECIFICATIONS & PROPERTIES
Purity:98%
Available Spectra:FT-IR, LCMS
Physical Form:White to off-white powder
Melting Point:234-238°C
Long-Term Storage:Store at room temperature

BIOLOGICAL INFO
Solubility:H2O: 50mg/mL; EtOH: insoluble
Application(s):Nitric oxide synthase (NOS) inhibitor; NMDA-activated ion channels blocker
Form:Sulfate salt

REVIEW

 Agmatine sulfate is a natural metabolite salt of the amino acid arginine. It is formed when arginine is decarboxylated by the enzyme arginine decarboxylase and is found naturally. Some of the biochemical mechanisms discovered so far concern agmatine's indication for diabetes, neuroprotection, and psychiatric conditions.

REFERENCES
[1]Su, Rui-Bin; Wang, Wei-Ping; Lu, Xin-Qiang; Wu, Ning; Liu, Zhi-Min; Li, Jin. Agmatine blocks acquisition and re-acquisition of intravenous morphine self-administration in rats. Pharmacology, Biochemistry and Behavior. (2009) 92(4): 676-682.
[2] Kotagale, Nandkishor Ramdas; Shirbhate, Saurabh Haridas; Shukla, Pradeep; Ugale, Rajesh Ramesh. Agmatine attenuates neuropathic pain in sciatic nerve ligated rats: Modulation by hippocampal sigma receptors. European Journal of Pharmacology. (2013) 714(1-3): 424-431.
[3] Kotagale, Nandkishor R.; Taksande, Brijesh G.; Wadhwani, Paresh J.; Palhade, Mahesh W.; Mendhi, Sachin M.; Gawande, Dinesh Y.; Hadole, Pravin N.; Chopde, Chandrabhan T. Psychopharmacological study of agmatine in behavioral tests of schizophrenia in rodents. Pharmacology, Biochemistry and Behavior. (2012) 100(3): 398-403.
[4] Golding, Bernard T.; Griffin, Roger J.; Mitchinson, Andrew; O'Sullivan, Mary C.New Routes to polyamine analogs Biochemical Society Transactions (1994), 22(4), 391S.

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P280; P305+P351+P338; P304+P340; P405; P501


RELATED PRODUCTS
X3130Agmatine dihydrochloride
P087Agmatine sulfate

Current as of December 7, 2016


Download SDS

CATEGORIES

 APIs and Bioactives >

USEFUL LINKS

  PubChem