P087 Agmatine sulfate - AK Scientific
 
 
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  Catalog ID # P087
Agmatine sulfate
, 98%
 
1-Amino-4-guanidinobutane sulfate salt
4-Guanidinobutylamine sulfate salt
N-(4-Aminobutyl)guanidine sulfate salt




IDENTITY
CAS Registry #:[2482-00-0]
MDL Number:MFCD00013109
MF:C5H16N4O4S
MW:228.27
EINECS:219-617-3
SPECIFICATIONS & PROPERTIES
Purity:98%
Available Spectra:FT-IR, LCMS
Physical Form:White to off-white powder
Melting Point:234-238°C
Long-Term Storage:Store at room temperature
Shipping:Not Regulated for Shipping

BIOLOGICAL INFO
Solubility:H2O: 50mg/mL; EtOH: insoluble
Application(s):Nitric oxide synthase (NOS) inhibitor; NMDA-activated ion channels blocker
Form:Sulfate salt

REVIEW

 Agmatine sulfate is a natural metabolite salt of the amino acid arginine. It is formed when arginine is decarboxylated by the enzyme arginine decarboxylase and is found naturally. Some of the biochemical mechanisms discovered so far concern agmatine's indication for diabetes, neuroprotection, and psychiatric conditions.

REFERENCES
[1]Su, Rui-Bin; Wang, Wei-Ping; Lu, Xin-Qiang; Wu, Ning; Liu, Zhi-Min; Li, Jin. Agmatine blocks acquisition and re-acquisition of intravenous morphine self-administration in rats. Pharmacology, Biochemistry and Behavior. (2009) 92(4): 676-682.
[2] Kotagale, Nandkishor Ramdas; Shirbhate, Saurabh Haridas; Shukla, Pradeep; Ugale, Rajesh Ramesh. Agmatine attenuates neuropathic pain in sciatic nerve ligated rats: Modulation by hippocampal sigma receptors. European Journal of Pharmacology. (2013) 714(1-3): 424-431.
[3] Kotagale, Nandkishor R.; Taksande, Brijesh G.; Wadhwani, Paresh J.; Palhade, Mahesh W.; Mendhi, Sachin M.; Gawande, Dinesh Y.; Hadole, Pravin N.; Chopde, Chandrabhan T. Psychopharmacological study of agmatine in behavioral tests of schizophrenia in rodents. Pharmacology, Biochemistry and Behavior. (2012) 100(3): 398-403.
[4] Golding, Bernard T.; Griffin, Roger J.; Mitchinson, Andrew; O'Sullivan, Mary C.New Routes to polyamine analogs Biochemical Society Transactions (1994), 22(4), 391S.

Risk Description(s)
R36/37/38:Irritating to eyes, respiratory system and skin

Safety Description(s)
S24/25:Avoid contact with skin and eyes.


Pricing

RELATED PRODUCTS
X3130Agmatine dihydrochloride
P087Agmatine sulfate

CURRENT AS OF: September 26, 2016

Availability
1. Backordered: Please contact us for availability.
2. All prices FOB San Francisco, USA

HazMat
HazMat shipping information is based on IATA/DOT regulations. All of the information is for reference only and subject to change without notice.

Quality
1. All products' quality is guaranteed.
2. Lot-specific spectra and CoA available on request.

Usage
AK Scientific products are intended for Research and Development usage only. The products are not to be used for other purposes, including, but not limited to, human or animal use, or as a component in, a food, drug, medical device (including in vitro diagnostic reagents), cosmetics and pesticides.

The hazards associated with this chemical have not been fully evaluated. This chemical is to be used for research and development purposes only, under the supervision of a technically qualified individual.

AK Scientific is not an EPA registered pesticidal establishment. Our products are not intended for pesticidal applications.

SDS

 P087_SDS.pdf

CATEGORIES

 APIs and Bioactives >

USEFUL LINKS

  PubChem