P087 Agmatine sulfate - AK Scientific
 
 
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  Catalog ID # P087
Agmatine sulfate
, 98%
 
1-Amino-4-guanidinobutane sulfate salt
4-Guanidinobutylamine sulfate salt
N-(4-Aminobutyl)guanidine sulfate salt




IDENTITY
CAS Registry #:[2482-00-0]
MDL Number:MFCD00013109
MF:C5H16N4O4S
MW:228.27
EINECS:219-617-3
SPECIFICATIONS & PROPERTIES
Purity:98%
Physical Form:White to off-white powder
Melting Point:234-238°C
Shipping:Not Regulated for Shipping.

BIOLOGICAL INFO
Solubility:H2O: 50mg/mL; EtOH: insoluble
Application(s):Nitric oxide synthase (NOS) inhibitor; NMDA-activated ion channels blocker
Form:Sulfate salt

REVIEW

 Agmatine sulfate is a natural metabolite salt of the amino acid arginine. It is formed when arginine is decarboxylated by the enzyme arginine decarboxylase and is found naturally. Some of the biochemical mechanisms discovered so far concern agmatine's indication for diabetes, neuroprotection, and psychiatric conditions.

REFERENCES
[1]Su, Rui-Bin; Wang, Wei-Ping; Lu, Xin-Qiang; Wu, Ning; Liu, Zhi-Min; Li, Jin. Agmatine blocks acquisition and re-acquisition of intravenous morphine self-administration in rats. Pharmacology, Biochemistry and Behavior. (2009) 92(4): 676-682.
[2] Kotagale, Nandkishor Ramdas; Shirbhate, Saurabh Haridas; Shukla, Pradeep; Ugale, Rajesh Ramesh. Agmatine attenuates neuropathic pain in sciatic nerve ligated rats: Modulation by hippocampal sigma receptors. European Journal of Pharmacology. (2013) 714(1-3): 424-431.
[3] Kotagale, Nandkishor R.; Taksande, Brijesh G.; Wadhwani, Paresh J.; Palhade, Mahesh W.; Mendhi, Sachin M.; Gawande, Dinesh Y.; Hadole, Pravin N.; Chopde, Chandrabhan T. Psychopharmacological study of agmatine in behavioral tests of schizophrenia in rodents. Pharmacology, Biochemistry and Behavior. (2012) 100(3): 398-403.
[4] Golding, Bernard T.; Griffin, Roger J.; Mitchinson, Andrew; O'Sullivan, Mary C.New Routes to polyamine analogs Biochemical Society Transactions (1994), 22(4), 391S.

Risk Description(s)
R36/37/38:Irritating to eyes, respiratory system and skin

Safety Description(s)
S24/25:Avoid contact with skin and eyes.


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RELATED PRODUCTS
X3130Agmatine dihydrochloride
P087Agmatine sulfate

CURRENT AS OF: May 27, 2015
Availability
1. In Stock: Order today by 4 PM PT and ships today from San Francisco, CA, USA
2. Backordered: Please contact us for availability.
3. If Bulk (kg) is Backordered, sizes less than 1kg may be available.
4. All prices FOB San Francisco, CA, USA
HazMat
HazMat shipping information is based on IATA/DOT regulations. For reference only.
1. Not Required: Not regulated by IATA/DOT. Normal shipping for Ground and Express.
2. Required for Express: HazMat shipping via Express. Normal shipping for continental Ground.

SDS

 P087_SDS.pdf

CATEGORIES

 APIs and Bioactives >

USEFUL LINKS

  PubChem