M047 beta-Sitosterol - AK Scientific
 
 
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  Catalog ID # M047
beta-Sitosterol
, >80% (GC)
 



IDENTITY
CAS Registry #:[83-46-5]
MDL Number:MFCD00003631
MF:C29H50O
MW:414.71
EINECS:201-480-6
BRN:1916165
SPECIFICATIONS & PROPERTIES
Purity:>80% (GC)
Available Spectra:FT-IR, GCMS, GC
Grade:Technical grade
Physical Form:White to beige crystalline powder
Melting Point:136-142°C
Optical Rotation:-33° - -39° (c=0.5, CHCl3)
Long-Term Storage:Store long-term at -20°C
Shipping:Not Regulated for Shipping

BIOLOGICAL INFO
Application(s):Phytosterols

REVIEW

 Beta-Sitosterol is one of several phytosterols related to cholesterol. It reduces blood levels of cholesterol by competing with it for absorption in the intestine and is sometimes used in treating hypercholesterolemia. Due to its structural similarity to cholesterol, when sitosterol is absorbed in the intestine, it is transported by lipoproteins and incorporated into the cellular membrane. It takes the place of dietary and biliary cholesterol in micelles produced in the intestinal lumen.

REFERENCES
[1]Geoffroy, Philippe; Julien-David, Diane; Marchioni, Eric; Raul, Francis; Aoude-Werner, Dalal; Miesch, Michel Synthesis of highly pure oxyphytosterols and (oxy)phytosterol esters Steroids (2008), 73(7), 702-707.
[2] Hang, Jiliang; Dussault, Patrick A concise synthesis of beta-sitosterol and other phytosterols Steroids (2010), 75(12), 879-883.
[3] Berges RR, Windeler J, Trampisch HJ, Senge T. Randomised, placebo-controlled, double-blind clinical trial of beta-sitosterol in patients with benign prostatic hyperplasia. Beta-sitosterol Study Group. Lancet. 1995 Jun 17;345(8964):1529-32.
[4] Wilt TJ, MacDonald R, Ishani A.beta-sitosterol for the treatment of benign prostatic hyperplasia: a systematic review. BJU Int. 1999 Jun;83(9):976-83.

Risk Description(s)
R36/37/38:Irritating to eyes, respiratory system and skin

Safety Description(s)
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes.


Pricing

CURRENT AS OF: May 25, 2016

Availability
1. Backordered: Please contact us for availability.
2. All prices FOB San Francisco, USA

HazMat
HazMat shipping information is based on IATA/DOT regulations. All of the information is for reference only and subject to change without notice.

Quality
1. All products' quality is guaranteed.
2. Lot-specific spectra and CoA available on request.

Usage
AK Scientific products are intended for Research and Development usage only. The products are not to be used for other purposes, including, but not limited to, human or animal use, or as a component in, a food, drug, medical device (including in vitro diagnostic reagents), cosmetics and pesticides.

The hazards associated with this chemical have not been fully evaluated. This chemical is to be used for research and development purposes only, under the supervision of a technically qualified individual.

AK Scientific is not an EPA registered pesticidal establishment. Our products are not intended for pesticidal applications.

SDS

 M047_SDS.pdf

CATEGORIES

 APIs and Bioactives > Hypercholesterolemia

USEFUL LINKS

  PubChem