[660-27-5] Diisopropylammonium dichloroacetate AKSci K077
 
 
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  Catalog ID # K077
Diisopropylammonium dichloroacetate
, 95%
 
Vasculopatina
Dipromonium
Cubisol
more..




IDENTITY
CAS Number:[660-27-5]
MDL Number:MFCD00868288
MF:C8H17Cl2NO2
MW:230.13
EINECS:211-538-2
SPECIFICATIONS & PROPERTIES
Purity:95%
Physical Form:White crystalline powder
Long-Term Storage:Store at room temperature
Note:Manual review is required before order is released.

REVIEW

 Diisopropylammonium dichloroacetate is a vasodilator, and the active principle of pangamic acid. It has also been found to exert a significant and prolonged hypoglycemic effect in alloxan diabetic rats, but did not alter blood sugar levels of normal rats. It did not affect blood glycerol levels in either the diabetic or nondiabetic group. By suppressing fatty acid oxidation in muscle, it may reduce citrate levels and reactivate phosphofructokinase.

REFERENCES
[1]Santi, R.; Contessa, A. R.; Cozzari, L. Vantaggi. Pharmacologic action of diisopropylammonium dichloroacetate. Minerva Medica. (1960) 51: 2909-19.
[2] Stacpoole PW, Felts JM. Diisopropylammonium dichloroacetate (DIPA) and sodium dichloracetate (DCA): effect on glucose and fat metabolism in normal and diabetic tissue. Metabolism. (1970) Jan;19(1): 71-8.
[3] Kitamura N; Ota Y; Mimura K. Effects of diisopropylamine dichloroacetate on proliferation and differentiation of normal human keratinocytes in vitro. Skin Pharmacology and Applied Skin Physiology (1999) 12(6): 317-25.
[4] Diisopropylammonium salts (1958), DE 1105877 19580804.

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H302; H315; H319; H335

Precautionary Statements
P261; P280; P305+P351+P338; P304+P340; P405; P501


Current as of December 8, 2016


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