K077 Diisopropylammonium dichloroacetate - AK Scientific
 
 
Loading Please Wait...
  Catalog ID # K077
Diisopropylammonium dichloroacetate
, 95%
 
Vasculopatina
Dipromonium
Cubisol
Dapocel
Disotat
Kalodil
Oxypangam
Tensicor
Dedyl
Diisopropylamine dichloroacetate




IDENTITY
CAS Registry #:[660-27-5]
MDL Number:MFCD00868288
MF:C8H17Cl2NO2
MW:230.13
EINECS:211-538-2
SPECIFICATIONS & PROPERTIES
Purity:95%
Physical Form:White crystalline powder
Shipping:Not Regulated for Shipping
Note:Manual review is required before order is released.

REVIEW

 Diisopropylammonium dichloroacetate is a vasodilator, and the active principle of pangamic acid. It has also been found to exert a significant and prolonged hypoglycemic effect in alloxan diabetic rats, but did not alter blood sugar levels of normal rats. It did not affect blood glycerol levels in either the diabetic or nondiabetic group. By suppressing fatty acid oxidation in muscle, it may reduce citrate levels and reactivate phosphofructokinase.

REFERENCES
[1]Santi, R.; Contessa, A. R.; Cozzari, L. Vantaggi. Pharmacologic action of diisopropylammonium dichloroacetate. Minerva Medica. (1960) 51: 2909-19.
[2] Stacpoole PW, Felts JM. Diisopropylammonium dichloroacetate (DIPA) and sodium dichloracetate (DCA): effect on glucose and fat metabolism in normal and diabetic tissue. Metabolism. (1970) Jan;19(1): 71-8.
[3] Kitamura N; Ota Y; Mimura K. Effects of diisopropylamine dichloroacetate on proliferation and differentiation of normal human keratinocytes in vitro. Skin Pharmacology and Applied Skin Physiology (1999) 12(6): 317-25.
[4] Diisopropylammonium salts (1958), DE 1105877 19580804.

Risk Description(s)
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin

Safety Description(s)
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37:Wear suitable protective clothing and gloves.
S60:This material and its container must be disposed of as hazardous waste.



Pricing (not showing? please refresh your web browser)

CURRENT AS OF: June 30, 2015
Availability
1. In Stock: Order today by 4 PM PT and ships today from San Francisco, CA, USA
2. Backordered: Please contact us for availability.
3. If Bulk (kg) is Backordered, sizes less than 1kg may be available.
4. All prices FOB San Francisco, CA, USA
HazMat
HazMat shipping information is based on IATA/DOT regulations. For reference only.
1. Not Required: Not regulated by IATA/DOT. Normal shipping for Ground and Express.
2. Required for Express: HazMat shipping via Express. Normal shipping for continental Ground.

SDS

 K077_SDS.pdf

CATEGORIES

 APIs and Bioactives >

USEFUL LINKS

  PubChem