K077 Diisopropylammonium dichloroacetate - AK Scientific
 
 
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  Catalog ID # K077
Diisopropylammonium dichloroacetate
, 95%
 
Vasculopatina
Dipromonium
Cubisol
Dapocel
Disotat
Kalodil
Oxypangam
Tensicor
Dedyl
Diisopropylamine dichloroacetate




IDENTITY
CAS Registry #:[660-27-5]
MDL Number:MFCD00868288
MF:C8H17Cl2NO2
MW:230.13
EINECS:211-538-2
SPECIFICATIONS & PROPERTIES
Purity:95%
Physical Form:White crystalline powder
Long-Term Storage:Store at room temperature
Shipping:Not Regulated for Shipping
Note:Manual review is required before order is released.

REVIEW

 Diisopropylammonium dichloroacetate is a vasodilator, and the active principle of pangamic acid. It has also been found to exert a significant and prolonged hypoglycemic effect in alloxan diabetic rats, but did not alter blood sugar levels of normal rats. It did not affect blood glycerol levels in either the diabetic or nondiabetic group. By suppressing fatty acid oxidation in muscle, it may reduce citrate levels and reactivate phosphofructokinase.

REFERENCES
[1]Santi, R.; Contessa, A. R.; Cozzari, L. Vantaggi. Pharmacologic action of diisopropylammonium dichloroacetate. Minerva Medica. (1960) 51: 2909-19.
[2] Stacpoole PW, Felts JM. Diisopropylammonium dichloroacetate (DIPA) and sodium dichloracetate (DCA): effect on glucose and fat metabolism in normal and diabetic tissue. Metabolism. (1970) Jan;19(1): 71-8.
[3] Kitamura N; Ota Y; Mimura K. Effects of diisopropylamine dichloroacetate on proliferation and differentiation of normal human keratinocytes in vitro. Skin Pharmacology and Applied Skin Physiology (1999) 12(6): 317-25.
[4] Diisopropylammonium salts (1958), DE 1105877 19580804.

Risk Description(s)
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin

Safety Description(s)
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37:Wear suitable protective clothing and gloves.
S60:This material and its container must be disposed of as hazardous waste.



Pricing

CURRENT AS OF: May 1, 2016

Availability
1. Backordered: Please contact us for availability.
2. All prices FOB San Francisco, USA

HazMat
HazMat shipping information is based on IATA/DOT regulations. All of the information is for reference only and subject to change without notice.

Quality
1. All products' quality is guaranteed.
2. Lot-specific spectra and CoA available on request.

Usage
AK Scientific products are intended for Research and Development usage only. The products are not to be used for other purposes, including, but not limited to, human or animal use, or as a component in, a food, drug, medical device (including in vitro diagnostic reagents), cosmetics and pesticides.

The hazards associated with this chemical have not been fully evaluated. This chemical is to be used for research and development purposes only, under the supervision of a technically qualified individual.

AK Scientific is not an EPA registered pesticidal establishment. Our products are not intended for pesticidal applications.

SDS

 K077_SDS.pdf

CATEGORIES

 APIs and Bioactives >

USEFUL LINKS

  PubChem