H967 Tranexamic acid - AK Scientific
 
 
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  Catalog ID # H967
Tranexamic acid
, 98% (HPLC)
 
trans-4-(Aminomethyl)cyclohexanecarboxylic acid
AMCA
AMCHA
HAKU
TAMCHA




IDENTITY
CAS Registry #:[1197-18-8]
MDL Number:MFCD00001466
MF:C8H15NO2
MW:157.21
EINECS:214-818-2
SPECIFICATIONS & PROPERTIES
Purity:98% (HPLC)
Available Spectra:NMR, LCMS, HPLC
Physical Form:White to off-white crystalline powder or powder
Melting Point:>300°C
Long-Term Storage:Store at room temperature
Shipping:Not Regulated for Shipping

REVIEW

 Tranexamic acid competitively inhibits activation of plasminogen via binding to the kringle domain, thereby reducing conversion of plasminogen to plasmin (fibrinolysin), an enzyme that degrades fibrin clots, fibrinogen, and other plasma proteins, including the procoagulant factors V and VIII. Tranexamic acid also directly inhibits plasmin activity, but higher doses are required than are needed to reduce plasmin formation.

REFERENCES
[1]Wellington K, Wagstaff AJ. Tranexamic acid: a review of its use in the management of menorrhagia. Drugs. 2003;63(13):1417-33.
[2] Arayne, M. Saeed; Journal of Molecular Structure 2008, V891(1-3), P475-480

Risk Description(s)
R36/37/38:Irritating to eyes, respiratory system and skin

Safety Description(s)
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.



Pricing

CURRENT AS OF: May 24, 2016

Availability
1. Backordered: Please contact us for availability.
2. All prices FOB San Francisco, USA

HazMat
HazMat shipping information is based on IATA/DOT regulations. All of the information is for reference only and subject to change without notice.

Quality
1. All products' quality is guaranteed.
2. Lot-specific spectra and CoA available on request.

Usage
AK Scientific products are intended for Research and Development usage only. The products are not to be used for other purposes, including, but not limited to, human or animal use, or as a component in, a food, drug, medical device (including in vitro diagnostic reagents), cosmetics and pesticides.

The hazards associated with this chemical have not been fully evaluated. This chemical is to be used for research and development purposes only, under the supervision of a technically qualified individual.

AK Scientific is not an EPA registered pesticidal establishment. Our products are not intended for pesticidal applications.

SDS

 H967_SDS.pdf

CATEGORIES

 Amino Acids > Unnatural Amino Acids
 APIs and Bioactives > Antihemorrhagics

USEFUL LINKS

  PubChem