[1197-18-8] Tranexamic acid AKSci H967
 
 
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  Catalog ID # H967
Tranexamic acid
, 98% (HPLC)
 
trans-4-(Aminomethyl)cyclohexanecarboxylic acid
AMCA
AMCHA
more..




IDENTITY
CAS Number:[1197-18-8]
MDL Number:MFCD00001466
MF:C8H15NO2
MW:157.21
EINECS:214-818-2
SPECIFICATIONS & PROPERTIES
Purity:98% (HPLC)
Available Spectra:NMR, LCMS, HPLC
Physical Form:White to off-white crystalline powder or powder
Melting Point:>300°C
Long-Term Storage:Store at room temperature

REVIEW

 Tranexamic acid competitively inhibits activation of plasminogen via binding to the kringle domain, thereby reducing conversion of plasminogen to plasmin (fibrinolysin), an enzyme that degrades fibrin clots, fibrinogen, and other plasma proteins, including the procoagulant factors V and VIII. Tranexamic acid also directly inhibits plasmin activity, but higher doses are required than are needed to reduce plasmin formation.

REFERENCES
[1]Wellington K, Wagstaff AJ. Tranexamic acid: a review of its use in the management of menorrhagia. Drugs. 2003;63(13):1417-33.
[2] Arayne, M. Saeed; Journal of Molecular Structure 2008, V891(1-3), P475-480

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of December 7, 2016


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CATEGORIES

 Amino Acids > Unnatural Amino Acids
 APIs and Bioactives > Antihemorrhagics

USEFUL LINKS

  PubChem