H789 Procaine HCl - AK Scientific
 
 
Loading Please Wait...
  Catalog ID # H789
Procaine HCl
, 97% (HPLC)
 
4-Aminobenzoic acid 2-(diethylamino)ethyl ester hydrochloride
2-(Diethylamino)ethyl 4-aminobenzoate hydrochloride
Novocaine hydrochloride




IDENTITY
CAS Registry #:[51-05-8]
MDL Number:MFCD00013000
MF:C13H21ClN2O2
MW:272.77
EINECS:200-077-2
BRN:3917802
SPECIFICATIONS & PROPERTIES
Purity:97% (HPLC)
Available Spectra:LCMS, HPLC
Physical Form:White to off-white crystalline powder
Melting Point:153-158°C
Boiling Point:195-196°C (17mmHg)
Long-Term Storage:Store long-term at 2-8°C
Shipping:Regulated for Shipping
UN #:UN2811
Hazard Class:6.1
Packing Group:III

BIOLOGICAL INFO
Form:HCl salt

REVIEW

 Procaine acts mainly by inhibiting sodium influx through voltage gated sodium channels in the neuronal cell membrane of peripheral nerves. When the influx of sodium is interrupted, an action potential cannot arise and signal conduction is thus inhibited. The receptor site is thought to be located at the cytoplasmic (inner) portion of the sodium channel. Procaine has also been shown to bind or antagonize the function of N-methyl-D-aspartate (NMDA) receptors as well as nicotinic acetylcholine receptors and the serotonin receptor-ion channel complex.

REFERENCES
[1]Gentry CL, Lukas RJ: Local anesthetics noncompetitively inhibit function of four distinct nicotinic acetylcholine receptor subtypes. J Pharmacol Exp Ther. 2001 Dec;299(3):1038-48.

Risk Description(s)
R25:Toxic if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin
R43:May cause sensitization by skin contact.

Safety Description(s)
S20:When using do not eat or drink.
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
S60:This material and its container must be disposed of as hazardous waste.



Pricing

RELATED PRODUCTS
H789Procaine HCl
M850Procainamide HCl
X4422Procaine

CURRENT AS OF: August 29, 2016

Availability
1. Backordered: Please contact us for availability.
2. All prices FOB San Francisco, USA

HazMat
HazMat shipping information is based on IATA/DOT regulations. All of the information is for reference only and subject to change without notice.

Quality
1. All products' quality is guaranteed.
2. Lot-specific spectra and CoA available on request.

Usage
AK Scientific products are intended for Research and Development usage only. The products are not to be used for other purposes, including, but not limited to, human or animal use, or as a component in, a food, drug, medical device (including in vitro diagnostic reagents), cosmetics and pesticides.

The hazards associated with this chemical have not been fully evaluated. This chemical is to be used for research and development purposes only, under the supervision of a technically qualified individual.

AK Scientific is not an EPA registered pesticidal establishment. Our products are not intended for pesticidal applications.

SDS

 H789_SDS.pdf

CATEGORIES

 APIs and Bioactives > Anaesthetics

USEFUL LINKS

  PubChem