[51-05-8] Procaine HCl AKSci H789
 
 
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  Catalog ID # H789
Procaine HCl
, 97% (HPLC)
 
4-Aminobenzoic acid 2-(diethylamino)ethyl ester hydrochloride
2-(Diethylamino)ethyl 4-aminobenzoate hydrochloride
Novocaine hydrochloride




IDENTITY
CAS Number:[51-05-8]
MDL Number:MFCD00013000
MF:C13H21ClN2O2
MW:272.77
EINECS:200-077-2
BRN:3917802
SPECIFICATIONS & PROPERTIES
Purity:97% (HPLC)
Available Spectra:LCMS, HPLC
Physical Form:White to off-white crystalline powder
Melting Point:153-158°C
Boiling Point:195-196°C (17mmHg)
Long-Term Storage:Store long-term at 2-8°C
UN #:UN2811
Hazard Class:6.1
Packing Group:III

BIOLOGICAL INFO
Form:HCl salt

REVIEW

 Procaine acts mainly by inhibiting sodium influx through voltage gated sodium channels in the neuronal cell membrane of peripheral nerves. When the influx of sodium is interrupted, an action potential cannot arise and signal conduction is thus inhibited. The receptor site is thought to be located at the cytoplasmic (inner) portion of the sodium channel. Procaine has also been shown to bind or antagonize the function of N-methyl-D-aspartate (NMDA) receptors as well as nicotinic acetylcholine receptors and the serotonin receptor-ion channel complex.

REFERENCES
[1]Gentry CL, Lukas RJ: Local anesthetics noncompetitively inhibit function of four distinct nicotinic acetylcholine receptor subtypes. J Pharmacol Exp Ther. 2001 Dec;299(3):1038-48.

GHS

Pictograms

Signal Word
Danger

Hazard Statements
H301; H317

Precautionary Statements
P261; P264; P270; P272; P280; P301+P310; P302+P352; P321; P330; P333+P313; P363; P405; P501


RELATED PRODUCTS
H789Procaine HCl
M850Procainamide HCl
X4422Procaine

Current as of December 4, 2016


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CATEGORIES

 APIs and Bioactives > Anaesthetics

USEFUL LINKS

  PubChem