H751 2-Mercaptoethanesulfonic acid sodium salt - AK Scientific
 
 
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  Catalog ID # H751
2-Mercaptoethanesulfonic acid sodium salt
, 95%
 
Sodium 2-mercaptoethanesulfonate
Coenzyme M sodium salt
Uromitexan
Mesnex
Mesna




IDENTITY
CAS Registry #:[19767-45-4]
MDL Number:MFCD00007535
MF:C2H5NaO3S2
MW:164.18
EINECS:243-285-9
SPECIFICATIONS & PROPERTIES
Purity:95%
Available Spectra:NMR, FT-IR
Physical Form:White to light yellow powder
Melting Point:259-275°C
Long-Term Storage:Store at room temperature
Shipping:Not Regulated for Shipping

BIOLOGICAL INFO
Solubility:DMSO: 33mg/mL; H2O: 7mg/mL; EtOH: <1mg/mL
Application(s):Hemorrhagic cystitis inhibitor
Form:Free Base

REVIEW

 An organosulfur compound used in cancer chemotherapy involving cyclophosphamide and ifosfamide as an adjuvant. Mesna is used therapeutically to reduce the incidence of haemorrhagic cystitis and haematuria when a patient receives ifosfamide or cyclophosphamide for cancer chemotherapy.

REFERENCES
[1]Vepachedu VR, Ferry JG (2012). Role of the fused corrinoid/methyl transfer protein CmtA during CO-dependent growth of Methanosarcina acetivorans. J Bacteriol. 194(16):4161-8. PMID 22636775.
[2] Cutler MJ, Urquhart BL, Velenosi TJ, Meyer Zu Schwabedissen HE, Dresser GK, Leake BF, Tirona RG, Kim RB, Freeman DJ (2012). In vitro and in vivo assessment of renal drug transporters in the disposition of mesna and dimesna. J Clin Pharmacol. 52(4):530-42. PMID 21505084.

Risk Description(s)
R36/37/38:Irritating to eyes, respiratory system and skin

Safety Description(s)
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.



Pricing

CURRENT AS OF: May 28, 2016

Availability
1. Backordered: Please contact us for availability.
2. All prices FOB San Francisco, USA

HazMat
HazMat shipping information is based on IATA/DOT regulations. All of the information is for reference only and subject to change without notice.

Quality
1. All products' quality is guaranteed.
2. Lot-specific spectra and CoA available on request.

Usage
AK Scientific products are intended for Research and Development usage only. The products are not to be used for other purposes, including, but not limited to, human or animal use, or as a component in, a food, drug, medical device (including in vitro diagnostic reagents), cosmetics and pesticides.

The hazards associated with this chemical have not been fully evaluated. This chemical is to be used for research and development purposes only, under the supervision of a technically qualified individual.

AK Scientific is not an EPA registered pesticidal establishment. Our products are not intended for pesticidal applications.

SDS

 H751_SDS.pdf

CATEGORIES

 APIs and Bioactives > Chemotherapeutics, Mucokinetics

USEFUL LINKS

  PubChem