72217-12-0 2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(methoxyimino)acetic acid AKSci H595
 
 
Loading Please Wait...
  H595    AKSci Bulk Reagent
2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(methoxyimino)acetic acid, 98% (HPLC)
 



IDENTITY
CAS Number:72217-12-0
MDL Number:MFCD07782101
MF:C5H6N4O3S
MW:202.19
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:179-183°C
Density:1.8
Refractive Index:1.74
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

REVIEW
 An advanced intermediate used in the preparation of side chains in beta-lactam cephalosporin and carbacephem antibiotics e.g. cefozopran.

REFERENCES
[1]Hashimoto, Masashi; Nakayama, Takarzuka; Hemmi, Keiji; Aratani, Matsuhiko; Takeno, Hidekazu; Hagiwara, Daijiro Cephalosporin analogs Ger. Offen. (1979), DE 2855418 A1 19790705.
[2] Teraji, Tsutomu; Sakane, Kazuo; Goto, Jiro 2-Substituted hydroxyimino-2-(5-amino-1,2,4-thiadiazol-3-yl)acetic acid or its salt and their intermediates Brit. UK Pat. Appl. (1982), GB 2094794 A 19820922.
[3] Teraji, Tsutomu; Sakane, Kazuo; Goto, Jiro 2-Substituted hydroxyimino-2-(5-amino-1,2,4-thiadiazol-3-yl)acetic acid or its salt and their intermediates Brit. UK Pat. Appl. (1982), GB 2094794 A 19820922.
[4] Kanai, Takeo; Takayanagi, Keizo; Tanaka, Yasuhide; Koiwa, Atsushi; Endo, Shinichi; Sato, Katsuhiko; Nomoto, Seiichiro; Sugiyama, Isao Preparation of 1,2,4-thiadiazolyl(alkoxyimino)acetic acids as intermediates for cephalosporins Jpn. Kokai Tokkyo Koho (1987), JP 62286979 A 19871212.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

RELATED PRODUCTS
H5952-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(methoxyimino)acetic acid
X4778(Z)-2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(ethoxyimino)acetic acid

Current as of April 23, 2024


Download SDS Request COA

All products are stocked and shipped from San Francisco Bay Area, California, USA.

⚠️
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.


CATEGORIES
 APIs and Bioactives > Cephalosporins
 Heterocyclic Building Blocks > Thiazoles, Carboxylic Acids, Amines, Ethers, Imine
 Heterocyclic Building Blocks > Thiazoles, Carboxylic Acids, Amines, Ethers, Imine


PubChem