F624 Diltiazem HCl - AK Scientific
 
 
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  Catalog ID # F624
Diltiazem HCl
, 97% (HPLC)
 
(+)-cis-Diltiazem hydrochloride
(2S,3S)-(+)-cis-3-Acetoxy-5-(2-dimethylaminoethyl)-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one hydrochloride, CRD-401




IDENTITY
CAS Registry #:[33286-22-5]
MDL Number:MFCD00069252
MF:C22H26N2O4S.HCl
MW:450.9788
EINECS:251-443-3
SPECIFICATIONS & PROPERTIES
Purity:97% (HPLC)
Available Spectra:NMR, HPLC, LCMS, Polarimetry
Physical Form:White to off-white powder
Melting Point:210-216°C
Optical Rotation:+114.0° - +122.0° (c=1, H2O)
Long-Term Storage:Store long-term at 2-8°C
Shipping:Not Regulated for Shipping

BIOLOGICAL INFO
Application(s):Benzothiazepine derivative
Form:HCl salt

REVIEW

 Possibly by deforming the channel, inhibiting ion-control gating mechanisms, and/or interfering with the release of calcium from the sarcoplasmic reticulum, diltiazem, like verapamil, inhibits the influx of extracellular calcium across both the myocardial and vascular smooth muscle cell membranes. The resultant inhibition of the contractile processes of the myocardial smooth muscle cells leads to dilation of the coronary and systemic arteries and improved oxygen delivery to the myocardial tissue.

Risk Description(s)
R22:Harmful if swallowed.

Safety Description(s)
S36:Wear suitable protective clothing.



Pricing

CURRENT AS OF: May 31, 2016

Availability
1. Backordered: Please contact us for availability.
2. All prices FOB San Francisco, USA

HazMat
HazMat shipping information is based on IATA/DOT regulations. All of the information is for reference only and subject to change without notice.

Quality
1. All products' quality is guaranteed.
2. Lot-specific spectra and CoA available on request.

Usage
AK Scientific products are intended for Research and Development usage only. The products are not to be used for other purposes, including, but not limited to, human or animal use, or as a component in, a food, drug, medical device (including in vitro diagnostic reagents), cosmetics and pesticides.

The hazards associated with this chemical have not been fully evaluated. This chemical is to be used for research and development purposes only, under the supervision of a technically qualified individual.

AK Scientific is not an EPA registered pesticidal establishment. Our products are not intended for pesticidal applications.

SDS

 F624_SDS.pdf

CATEGORIES

 APIs and Bioactives > Arrhythmia, Calcium Channel Blockers

USEFUL LINKS

  PubChem