E107 Tropicamide - AK Scientific
 
 
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  Catalog ID # E107
Tropicamide
, 98% (HPLC)
 
N-Ethyl-2-phenyl-N-(4-pyridylmethyl)hydracrylamide




IDENTITY
CAS Registry #:[1508-75-4]
MDL Number:MFCD00058580
MF:C17H20N2O2
MW:284.35
EINECS:216-140-2
SPECIFICATIONS & PROPERTIES
Purity:98% (HPLC)
Available Spectra:LCMS, HPLC
Physical Form:White crystalline powder
Melting Point:96-97°C
Long-Term Storage:Store at room temperature
Shipping:Not Regulated for Shipping

BIOLOGICAL INFO
Application(s):Anticholinergic and a muscarinic receptor subtype M4-preferring antagonist

REVIEW

 Tropicamide binds to and blocks the receptors in the muscles of the eye (muscarinic receptor M4). Tropicamide acts by blocking the responses of the iris sphincter muscle to the iris and ciliary muscles to cholinergic stimulation, producing dilation of the pupil and paralysis of the ciliary muscle.

REFERENCES
[1]Manny RE, Hussein M, Scheiman M, Kurtz D, Niemann K, Zinzer K (July 2001). Tropicamide (1%): an effective cycloplegic agent for myopic children. Investigative Ophthalmology & Visual Science 42 (8): 1728-35. PMID 11431435.

Risk Description(s)
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed
R36/37/38:Irritating to eyes, respiratory system and skin
R42/43:May cause sensitization by inhalation and skin contact

Safety Description(s)
S22:Do not breathe dust .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.



Pricing

CURRENT AS OF: September 29, 2016

Availability
1. Backordered: Please contact us for availability.
2. All prices FOB San Francisco, USA

HazMat
HazMat shipping information is based on IATA/DOT regulations. All of the information is for reference only and subject to change without notice.

Quality
1. All products' quality is guaranteed.
2. Lot-specific spectra and CoA available on request.

Usage
AK Scientific products are intended for Research and Development usage only. The products are not to be used for other purposes, including, but not limited to, human or animal use, or as a component in, a food, drug, medical device (including in vitro diagnostic reagents), cosmetics and pesticides.

The hazards associated with this chemical have not been fully evaluated. This chemical is to be used for research and development purposes only, under the supervision of a technically qualified individual.

AK Scientific is not an EPA registered pesticidal establishment. Our products are not intended for pesticidal applications.

SDS

 E107_SDS.pdf

CATEGORIES

 APIs and Bioactives > Ophthalmology, AChR Antagonists

USEFUL LINKS

  PubChem