[60-32-2] 6-Aminocaproic acid AKSci D007
 
 
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  Catalog ID # D007
6-Aminocaproic acid
, 99% (ELSD)
 
Aminocaproic acid
Amicar
6-aminohexanoic acid
more..




IDENTITY
CAS Number:[60-32-2]
MDL Number:MFCD00008238
MF:C6H13NO2
MW:131.17
EINECS:200-469-3
BRN:906872
SPECIFICATIONS & PROPERTIES
Purity:99% (ELSD)
Available Spectra:NMR, FT-IR, LCMS, HPLC
Physical Form:White crystalline powder
Melting Point:204-212°C
Long-Term Storage:Store long-term at 2-8°C

BIOLOGICAL INFO
Solubility:DMSO: 6mg/mL; H2O: 26mg/mL; EtOH: 1mg/mL
Application(s):Antifibrinolytic Agent; Proteolytic Enzyme Inhibitor
Form:Free Base

REVIEW

 Aminocaproic acid is used to treat excessive postoperative bleeding. It is a derivative and analogue of the amino acid lysine, which makes it an effective inhibitor for enzymes that bind that particular residue. Such enzymes include proteolytic enzymes like plasmin, the enzyme responsible for fibrinolysis.

REFERENCES
[1]Thondorf I, Voigt V, Schäfer S, Gebauer S, Zebisch K, Laug L, Brandsch M (2011). Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1). Bioorg Med Chem. 19(21):6409-18. PMID 21955456.
[2] Banerjee A, Stoica C, Walia A (2011). Acute hyperkalemia as a complication of intravenous therapy with epsilon-aminocaproic acid. J Clin Anesth. 23(7):565-8. PMID 22050802.



Current as of December 4, 2016


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CATEGORIES

 Amino Acids > Unnatural Amino Acids
 APIs and Bioactives > Antihemorrhagics

USEFUL LINKS

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