D007 6-Aminocaproic acid - AK Scientific
 
 
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  Catalog ID # D007
6-Aminocaproic acid
, 99% (ELSD)
 
Aminocaproic acid
Amicar
6-aminohexanoic acid
EACA




IDENTITY
CAS Registry #:[60-32-2]
MDL Number:MFCD00008238
MF:C6H13NO2
MW:131.17
EINECS:200-469-3
BRN:906872
SPECIFICATIONS & PROPERTIES
Purity:99% (ELSD)
Available Spectra:NMR, FT-IR, LCMS, HPLC
Physical Form:White crystalline powder
Melting Point:204-212°C
Long-Term Storage:Store long-term at 2-8°C
Shipping:Not Regulated for Shipping

BIOLOGICAL INFO
Solubility:DMSO: 6mg/mL; H2O: 26mg/mL; EtOH: 1mg/mL
Application(s):Antifibrinolytic Agent; Proteolytic Enzyme Inhibitor
Form:Free Base

REVIEW

 Aminocaproic acid is used to treat excessive postoperative bleeding. It is a derivative and analogue of the amino acid lysine, which makes it an effective inhibitor for enzymes that bind that particular residue. Such enzymes include proteolytic enzymes like plasmin, the enzyme responsible for fibrinolysis.

REFERENCES
[1]Thondorf I, Voigt V, Schäfer S, Gebauer S, Zebisch K, Laug L, Brandsch M (2011). Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1). Bioorg Med Chem. 19(21):6409-18. PMID 21955456.
[2] Banerjee A, Stoica C, Walia A (2011). Acute hyperkalemia as a complication of intravenous therapy with epsilon-aminocaproic acid. J Clin Anesth. 23(7):565-8. PMID 22050802.

Risk Description(s)
R36/37/38:Irritating to eyes, respiratory system and skin

Safety Description(s)
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.



Pricing

CURRENT AS OF: August 24, 2016

Availability
1. Backordered: Please contact us for availability.
2. All prices FOB San Francisco, USA

HazMat
HazMat shipping information is based on IATA/DOT regulations. All of the information is for reference only and subject to change without notice.

Quality
1. All products' quality is guaranteed.
2. Lot-specific spectra and CoA available on request.

Usage
AK Scientific products are intended for Research and Development usage only. The products are not to be used for other purposes, including, but not limited to, human or animal use, or as a component in, a food, drug, medical device (including in vitro diagnostic reagents), cosmetics and pesticides.

The hazards associated with this chemical have not been fully evaluated. This chemical is to be used for research and development purposes only, under the supervision of a technically qualified individual.

AK Scientific is not an EPA registered pesticidal establishment. Our products are not intended for pesticidal applications.

SDS

 D007_SDS.pdf

CATEGORIES

 Amino Acids > Unnatural Amino Acids
 APIs and Bioactives > Antihemorrhagics

USEFUL LINKS

  PubChem