C560 Prednisolone acetate - AK Scientific
 
 
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  Catalog ID # C560
Prednisolone acetate
, 98% (HPLC)
 
21-Acetoxy-1,4-pregnadiene-11beta,17alpha-diol-3,20-dione
Omnipred
Prednisolone 21-acetate




IDENTITY
CAS Registry #:[52-21-1]
MDL Number:MFCD00037710
MF:C23H30O6
MW:402.48
EINECS:200-134-1
BRN:3111798
SPECIFICATIONS & PROPERTIES
Purity:98% (HPLC)
Available Spectra:FT-IR, LCMS, HPLC, Polarimetry
Physical Form:White to off-white powder
Melting Point:245-252°C
Optical Rotation:+105 ~ +118° (c=1, Dioxane)
Long-Term Storage:Store at room temperature
Shipping:Regulated for Shipping
UN #:UN2811
Hazard Class:6.1
Packing Group:III

BIOLOGICAL INFO
Solubility:CHCl3:MeOH (1:1): 50mg/mL
Application(s):Anti-Inflammatory Agent; Glucocorticoid Receptors (GR)
Form:Free Base

REVIEW

 A synthetic glucocorticoid, a derivative of cortisol, which is used to treat a variety of inflammatory and auto-immune conditions. Prednisolone irreversibly binds with glucocorticoid receptors (GR) alpha and beta for which they have a high affinity.

REFERENCES
[1]McLean NJ, Ward DA, Hendrix DV, Vaughn RK (2012). Effects of one-week versus one-day preoperative treatment with topical 1% prednisolone acetate in dogs undergoing phacoemulsification. J Am Vet Med Assoc. 240(5):563-9. PMID 22332625.
[2] Nien CJ, Flynn KJ, Chang M, Brown D, Jester JV (2011). Reducing peak corneal haze after photorefractive keratectomy in rabbits: prednisolone acetate 1.00% versus cyclosporine A 0.05%. J Cataract Refract Surg. 37(5):937-44. PMID 21406325.

Risk Description(s)
R25:Toxic if swallowed.

Safety Description(s)
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).



Pricing

CURRENT AS OF: October 1, 2016

Availability
1. Backordered: Please contact us for availability.
2. All prices FOB San Francisco, USA

HazMat
HazMat shipping information is based on IATA/DOT regulations. All of the information is for reference only and subject to change without notice.

Quality
1. All products' quality is guaranteed.
2. Lot-specific spectra and CoA available on request.

Usage
AK Scientific products are intended for Research and Development usage only. The products are not to be used for other purposes, including, but not limited to, human or animal use, or as a component in, a food, drug, medical device (including in vitro diagnostic reagents), cosmetics and pesticides.

The hazards associated with this chemical have not been fully evaluated. This chemical is to be used for research and development purposes only, under the supervision of a technically qualified individual.

AK Scientific is not an EPA registered pesticidal establishment. Our products are not intended for pesticidal applications.

SDS

 C560_SDS.pdf

CATEGORIES

 APIs and Bioactives > Immunomodulators

USEFUL LINKS

  PubChem