C454 Icariin - AK Scientific
 
 
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  Catalog ID # C454
Icariin
, 98%
 
3-((6-Deoxymannopyranosyl)oxy)-7-(glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one
Leariline




IDENTITY
CAS Registry #:[489-32-7]
MDL Number:MFCD00210516
MF:C33H40O15
MW:676.66
BRN:76280
SPECIFICATIONS & PROPERTIES
Purity:98%
Physical Form:Light yellow to yellow powder
Melting Point:237-242°C
Long-Term Storage:Store long-term at 2-8°C
Shipping:Not Regulated for Shipping

BIOLOGICAL INFO
Solubility:DMSO: 50mg/mL
Application(s):PDE5 inhibitor

REVIEW

 The mechanism of action for chlorprothixene, like other thioxanthenes and phenothiazines, is not fully understood. The sites of action appear to be the reticular activating system of the midbrain, the limbic system, the hypothalamus, and the globus pallidus and corpus striatum. The mechanism appears to be one or more of a combination of postsynaptic blockade of adrenergic, dopaminergic, or serotonergic receptor sites, metabolic inhibition of oxidative phosphorylation, or decrease in the excitability of neuronal membranes.

REFERENCES
[1]Liu JJ, Li SP, Wang YT (January 2006). Optimization for quantitative determination of four flavonoids in Epimedium by capillary zone electrophoresis coupled with diode array detection using central composite design. J Chromatogr A 1103 (2): 344-9. doi:10.1016/j.chroma.2005.11.036. PMID 16337210.
[2] Makarova MN, Pozharitskaya ON, Shikov AN, Tesakova SV, Makarov VG, Tikhonov VP (December 2007). Effect of lipid-based suspension of Epimedium koreanum Nakai extract on sexual behavior in rats. J Ethnopharmacol 114 (3): 412-6. doi:10.1016/j.jep.2007.08.021. PMID 17890032.

Risk Description(s)
R36/37/38:Irritating to eyes, respiratory system and skin

Safety Description(s)
S24/25:Avoid contact with skin and eyes.


Pricing

CURRENT AS OF: May 27, 2016

Availability
1. Backordered: Please contact us for availability.
2. All prices FOB San Francisco, USA

HazMat
HazMat shipping information is based on IATA/DOT regulations. All of the information is for reference only and subject to change without notice.

Quality
1. All products' quality is guaranteed.
2. Lot-specific spectra and CoA available on request.

Usage
AK Scientific products are intended for Research and Development usage only. The products are not to be used for other purposes, including, but not limited to, human or animal use, or as a component in, a food, drug, medical device (including in vitro diagnostic reagents), cosmetics and pesticides.

The hazards associated with this chemical have not been fully evaluated. This chemical is to be used for research and development purposes only, under the supervision of a technically qualified individual.

AK Scientific is not an EPA registered pesticidal establishment. Our products are not intended for pesticidal applications.

SDS

 C454_SDS.pdf

CATEGORIES

 APIs and Bioactives > Flavonoids

USEFUL LINKS

  PubChem