REVIEW The mechanism of action for chlorprothixene, like other thioxanthenes and phenothiazines, is not fully understood. The sites of action appear to be the reticular activating system of the midbrain, the limbic system, the hypothalamus, and the globus pallidus and corpus striatum. The mechanism appears to be one or more of a combination of postsynaptic blockade of adrenergic, dopaminergic, or serotonergic receptor sites, metabolic inhibition of oxidative phosphorylation, or decrease in the excitability of neuronal membranes.
REFERENCES
[1]
Liu JJ, Li SP, Wang YT (January 2006). Optimization for quantitative determination of four flavonoids in Epimedium by capillary zone electrophoresis coupled with diode array detection using central composite design. J Chromatogr A 1103 (2): 344-9. doi:10.1016/j.chroma.2005.11.036. PMID 16337210.
[2]
Makarova MN, Pozharitskaya ON, Shikov AN, Tesakova SV, Makarov VG, Tikhonov VP (December 2007). Effect of lipid-based suspension of Epimedium koreanum Nakai extract on sexual behavior in rats. J Ethnopharmacol 114 (3): 412-6. doi:10.1016/j.jep.2007.08.021. PMID 17890032.
All products are stocked and shipped from San Francisco Bay Area, California, USA.
⚠️
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.
These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.
Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.
New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.
Add to Favorites 
Delete from Favorites 
